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| Cat. Number | A4002 |
| Chemical Name | A4002 AK-7 420831-40-9 |
| CAS Number | 420831-40-9 |
| Mol. Formula | C19H21BrN2O3S |
| Mol. Weight | 437.35 |
| Qty 1 |
5mg |
| Qty 2 | 25mg |
| Appearance | White to off white powder |
| Application Notes | ≥98% |
| Synonym | AK7 |
| Solubility | 100mM in DMSO |
| Storage condition | -20°C |
| References | AK-7 is an inhibitor of sirtuin 2 (SIRT2); sirtuins are considered class III histone deacetylases (HDACs). AK-7 exhibits neuroprotective activity, decreasing brain atrophy and improving motor function and survival in animal models of Huntington’s disease. ReferencesChopra V, Quinti L, Kim J, et al. The sirtuin 2 inhibitor AK-7 is neuroprotective in Huntington's disease mouse models. Cell Rep. 2012 Dec 27;2(6):1492-7. PMID: 23200855. |
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